VITAMINS E AND C INFLUENCE ON INDEXES OF OXIDATIVE STATUS OF RATS’ KIDNEY TISSUE AND BLOOD HAVING STREPTOZOTOCIN DIABETES
Krasnyi Mikhail Romanovich, Sergienko Viktoriya Aleksandrovna, Sergienko Aleksandr Alekseevich
Danylo Halytsky Lviv National Medical University, Ukraine
Abstract. The article is aimed at researching the peculiarities of vitamins Е and С influence on some indexes of the oxidative status of rats’ kidney tissue and blood having streptozotocin diabetes. It is ascertained that vitamins Е and С use was accompanied with the significant reduction of the level of the primary and final products of lipids peroxide oxidation, the normalization of the concentration of deoxidated proteins SH-groups and catalase activation in rats’ kidney tissue. The results of our research indicate that it is reasonable to use antioxidant vitamins Е and С for the normalization of general antioxidant status and some its components.
Key words and phrases: стрептозотоциновый диабет, почки, антиоксидантный статус, перекисное окисление липидов, витамины Е и С, streptozotocin diabetes, kidneys, antioxidant status, lipids peroxide oxidation, vitamins Е and С
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